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As a side observation, peak tailing is a much more common problem with LC separations. 009" tubing connects to.
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    Dependence of Retention Times on pH 16.

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    Mar 27, 2020 The main cause of this is usually poor solubility of the sample i.

  • Clean or replace the liner.
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    "Basic Tailing" can occur on all peaks if all analytes are basic Basic analytes will tail on a reverse-phase column via weak cation exchange if The pH of the mobile phase will allow the basic analyte to carry a positive charge.

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  • Insufficient buffering of mobile phase.
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    009" tubing connects to.

  • One of the best ways to resolve this issue is to lower the pH of the mobile phase to about.
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    Common causes of peak tailing andor low resolution include (but are not limited to) Presence of Teflon (PTFE) in the sample flow path.

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